Publications

Siebers R, Schultz D, Farza MS, Brauer A, Zühlke D, Mücke PA, Wang F, Bernhardt J, Teeling H, Becher D, Riedel K, Kirstein IV, Wiltshire KH, Hoff KJ, Schweder T, Urich T, Bengtsson MM. (2024)
Marine particle microbiomes during a spring diatom bloom contain active sulfate-reducing bacteria.
FEMS Microbiol Ecol.
https://doi.org/10.1093/femsec/fiae037

Wang FQ, Bartosik D, Sidhu C, Siebers R, Lu DC, Trautwein-Schult A, Becher D, Huettel B, Rick J, Kirstein IV, Wiltshire KH, Schweder T, Fuchs BM, Bengtsson MM, Teeling H, Amann RI. (2024)
Particle-attached bacteria act as gatekeepers in the decomposition of complex phytoplankton polysaccharides.
Microbiome. 12(1):32
https://doi.org/10.1186/s40168-024-01757-5

Dutschei T, Beidler I, Bartosik D, Seeßelberg JM, Teune M, Bäumgen M, Ferreira SQ, Heldmann J, Nagel F, Krull J, Berndt L, Methling K, Hein M, Becher D, Langer P, Delcea M, Lalk M, Lammers M, Höhne M, Hehemann JH, Schweder T, Bornscheuer UT. (2023)
Marine Bacteroidetes enzymatically digest xylans from terrestrial plants.
Environ Microbiol. 25(9):1713-1727

https://doi.org/10.1111/1462-2920.16390

Lu DC, Wang FQ, Amann RI, Teeling H, Du ZJ. (2023)
Epiphytic common core bacteria in the microbiomes of co-located green (Ulva), brown (Saccharina) and red (Grateloupia, Gelidium) macroalgae.
Microbiome. 11(1):126
https://doi.org/10.1186/s40168-023-01559-1

Sidhu C, Kirstein IV, Meunier CL, Rick J, Fofonova V, Wiltshire KH, Steinke N, Vidal-Melgosa S, Hehemann JH, Huettel B, Schweder T, Fuchs BM, Amann RI, Teeling H. (2023)
Dissolved storage glycans shaped the community composition of abundant bacterioplankton clades during a North Sea spring phytoplankton bloom.
Microbiome. 11(1):77
https://doi.org/10.1186/s40168-023-01517-x

Brott S, Nam KH, Thomas F, Dutschei T, Reisky L, Behrens M, Grimm HC, Michel G, Schweder T, Bornscheuer UT. (2023)
Unique alcohol dehydrogenases involved in algal sugar utilization by marine bacteria.
Appl Microbiol Biotechnol. 107(7-8):2363-2384

https://doi.org/10.1007/s00253-023-12447-x

Beidler I, Robb CS, Vidal-Melgosa S, Zühlke MK, Bartosik D, Solanki V, Markert S, Becher D, Schweder T, Hehemann JH. (2023)
Marine bacteroidetes use a conserved enzymatic cascade to digest diatom β-mannan.
ISME J. 17(2):276-285

https://doi.org/10.1038/s41396-022-01342-4

Dutschei T, Zühlke MK, Welsch N, Eisenack T, Hilkmann M, Krull J, Stühle C, Brott S, Dürwald A, Reisky L, Hehemann JH, Becher D, Schweder T, Bornscheuer UT. (2022)
Metabolic engineering enables Bacillus licheniformis to grow on the marine polysaccharide ulvan.
Microbial Cell Factories. 21(1):207

https://doi.org/10.1186/s12934-022-01931-0

Brott S, Thomas F, Behrens M, Methling K, Bartosik D, Dutschei T, Lalk M, Michel G, Schweder T, Bornscheuer U. (2022)
Connecting algal polysaccharide degradation to formaldehyde detoxification.
Chembiochem. 23(14):e202200269

https://doi.org/10.1002/cbic.202200269

Solanki V, Krüger K, Crawford CJ, Pardo-Vargas A, Danglad-Flores J, Hoang KLM, Klassen L, Abbott DW, Seeberger PH, Amann RI, Teeling H, Hehemann JH. (2022)
Glycoside hydrolase from the GH76 family indicates that marine Salegentibacter sp. Hel_I_6 consumes alpha-mannan from fungi.
ISME J. 16(7):1818-1830

https://doi.org/10.1038/s41396-022-01223-w

Pudlo NA, Pereira GV, Parnami J, Cid M, Markert S, Tingley JP, Unfried F, Ali A, Varghese NJ, Kim KS, Campbell A, Urs K, Xiao Y, Adams R, Martin D, Bolam DN, Becher D, Eloe-Fadrosh EA, Schmidt TM, Abbott DW, Schweder T, Hehemann JH, Martens EC. (2022)
Diverse events have transferred genes for edible seaweed digestion from marine to human gut bacteria.
Cell Host Microbe. 30(3):314-328.e11

https://doi.org/10.1016/j.chom.2022.02.001

Bäumgen M, Dutschei T, Bornscheuer UT. (2021)
Marine Polysaccharides: Occurrence, Enzymatic Degradation and Utilization.
Chembiochem. 22(13):2247-2256

https://doi.org/10.1002/cbic.202100078

Dürwald A, Zühlke MK, Schlüter R, Gebbe R, Bartosik D, Unfried F, Becher D, Schweder T. (2021)
Reaching out in anticipation: bacterial membrane extensions represent a permanent investment in polysaccharide sensing and utilization.
Environ. Microbiol. 23(6):3149-3163
https://doi.org/10.1111/1462-2920.15537

Bäumgen M, Dutschei T, Bartosik D, Suster C, Reisky L, Gerlach N, Stanetty C, Mihovilovic MD, Schweder T, Hehemann JH, Bornscheuer UT. (2021)
A new carbohydrate-active oligosaccharide dehydratase is involved in the degradation of ulvan.
J. Biol. Chem. 397(4):101210
https://doi.org/10.1016/j.jbc.2021.101210

Francis B, Urich T, Mikolasch A, Teeling H, Amann R. (2021)
North Sea spring bloom-associated Gammaproteobacteria fill diverse heterotrophic niches.
Environ. Microbiome. 16(1):15
https://doi.org/10.1186/s40793-021-00385-y

Heins A, Amann RI, Harder J. (2021)
Cultivation of particle-associated heterotrophic bacteria during a spring phytoplankton bloom in the North Sea.
Syst. Appl. Microbiol. 44(5):126232
https://doi.org/10.1016/j.syapm.2021.126232

Sichert A, Le Gall S, Klau LJ, Laillet B, Rogniaux H, Aachmann FL, Hehemann JH. (2021)
Ion-exchange purification and structural characterization of five sulfated fucoidans from brown algae.
Glycobiology 31(4):352-357
https://doi.org/10.1093/glycob/cwaa064

Heins A, Reintjes G, Amann RI, Harder J. (2021)
Particle Collection in Imhoff Sedimentation Cones Enriches Both Motile Chemotactic and Particle-Attached Bacteria.
Frontiers Microbiol. 12:643730
https://doi.org/10.3389/fmicb.2021.643730

Vidal-Melgosa S, Sichert A, Francis TB, Bartosik D, Niggemann J, Wichels A, Willats WGT, Fuchs BM, Teeling H, Becher D, Schweder T, Amann R, Hehemann JH. (2021)
Diatom fucan polysaccharide precipitates carbon during algal blooms.
Nature Commun. 12(1):1150
https://doi.org/10.1038/s41467-021-21009-6

Francis TB, Bartosik D, Sura T, Sichert A, Hehemann JH, Markert S, Schweder T, Fuchs BM, Teeling H, Amann RI, Becher D. (2021)
Changing expression patterns of TonB-dependent transporters suggest shifts in polysaccharide consumption over the course of a spring phytoplankton bloom.
ISME J. 15(8): 2336-2350 
https://doi.org/10.1038/s41396-021-00928-8

Klassen L, Reintjes G, Tingley JP, Jones DR, Hehemann JH, Smith AD, Schwinghamer TD, Arnosti C, Jin L, Alexander TW, Amundsen C, Thomas D, Amann R, McAllister TA, Abbott DW. (2021)
Quantifying fluorescent glycan uptake to elucidate strain-level variability in foraging behaviors of rumen bacteria.
Microbiome. 9:23
https://doi.org/10.1186/s40168-020-00975-x

Arnosti C, Wietz M, Brinkhoff T, Hehemann J-H, Probandt D, Zeugner L, Amann R. (2021)
The Biogeochemistry of Marine Polysaccharides: Sources, Inventories, and Bacterial Drivers of the Carbohydrate Cycle.
Ann Rev Mar Sci. 13:81-108
https://doi.org/10.1146/annurev-marine-032020-012810

Schultz D, Zühlke D, Bernhardt J, Francis TB, Albrecht D, Hirschfeld C, Markert S, Riedel K. (2020)
An optimized metaproteomics protocol for a holistic taxonomic and functional characterization of microbial communities from marine particles.
Environ Microbiol Rep. 12(4):367-376
https://doi.org/10.1111/1758-2229.12842

Giljan G, Kamennaya NA, Otto A, Becher D, Ellrott A, Meyer V, Murton BJ, Fuchs BM, Amann RI, Zubkov MV. (2020)
Bacterioplankton reveal years-long retention of Atlantic deep-ocean water by the Tropic Seamount.
Sci Rep. 10(1):4715
https://doi.org/10.1038/s41598-020-61417-0

Alejandre-Colomo C, Harder J, Fuchs BM, Rosselló-Móra R, Amann R. (2020)
High-throughput cultivation of heterotrophic bacteria during a spring phytoplankton bloom in the North Sea.
Syst Appl Microbiol. 43(2):126066
https://doi.org/10.1016/j.syapm.2020.126066

Grieb A, Francis TB, Krüger K, Orellana LH, Amann R, Fuchs BM. (2020)
Candidatus Abditibacter, a novel genus within the Cryomorphaceae, thriving in the North Sea.
Syst Appl Microbiol. 43(4):126088
https://doi.org/10.1016/j.syapm.2020.126088

Sichert A, Corzett CH, Schechter MS, Unfried F, Markert S, Becher D, Fernandez-Guerra A, Liebeke M, Schweder T, Polz MF, Hehemann JH. (2020)
Verrucomicrobia use hundreds of enzymes to digest the algal polysaccharide fucoidan.
Nature Microbiol. 5(8):1026-1039
https://doi.org/10.1038/s41564-020-0720-2

Becker S, Tebben J, Coffinet S, Wiltshire K, Iversen MH, Harder T, Hinrichs KU, Hehemann JH. (2020)
Laminarin is a major molecule in the marine carbon cycle.
Proc Natl Acad Sci U S A. 117(12):6599-6607.
https://doi.org/ 10.1073/pnas.1917001117

Fischer T, Schorb M, Reintjes G, Kolovou A, Santarella-Mellwig R, Markert S, Rhiel E, Littmann S, Becher D, Schweder T, Harder J. (2019)
Biopearling of Interconnected Outer Membrane Vesicle Chains by a Marine Flavobacterium.
Appl Environ Microbiol. 85(19). pii: e00829-19.
https://doi.org/10.1128/AEM.00829-19

Schada von Borzyskowski L, Severi F, Krüger K, Hermann L, Gilardet A, Sippel F, Pommerenke B, Claus P, Socorro Cortina N, Glatter T, Zauner S, Zarzycki J, Fuchs BM, Bremer E, Maier UG, Amann RI, Erb TJ. (2019)
Marine Proteobacteria metabolise glycolate via the β-hydroxyaspartate cycle.
Nature Vol. 575
https://doi.org/10.1038/s41586-019-1748-4

Krüger K, Chafee M, Francis TB, Glavina del Rio T,Becher D, Schweder T,Amann RI, Teeling H. (2019) 
In marine Bacteroidetes the bulk of algal glycan degradation during algae blooms is mediated by a few clades using a restricted set of genes.
ISME J. 13(11):2800-2816
https://doi.org/10.1038/s41396-019-0476-y

Reisky L, Préchoux A, Zühlke MK, Bäumgen M, Robb CS, Gerlach N, Roret T, Stanetty C, Larocque R, Michel G, Tao S, Markert S, Unfried F, Mihovilovic MD, Trautwein-Schult A, Becher D, Schweder T, Bornscheuer UT, Hehemann JH. (2019)
A marine bacterial enzymatic cascade degrades the algal polysaccharide ulvan.
Nature Chem Biol. 15(8):803-812
https://doi.org/10.1038/s41589-019-0311-9

Chen J, Robb CS, Unfried F, Kappelmann L, Markert S, Song T, Harder J, Avcı B, Becher D, Xie P, Amann RI, Hehemann JH, Schweder T, Teeling H. (2018)

Alpha- and beta-mannan utilization by marine Bacteroidetes.

Environ. Microbiol. 20(11):4127-4140
https://doi.org/10.1111/1462-2920.14414

Robb CS, Reisky L, Bornscheuer UT, Hehemann JH. (2018)

Specificity and mechanism of carbohydrate demethylation by cytochrome P450 monooxygenases.

Biochem. J. 475(23):3875-3886
https://doi.org/10.1042/BCJ20180762

Mystkowska AA, Robb C, Vidal-Melgosa S, Vanni C, Fernandez-Guerra A, Höhne M, Hehemann JH. (2018)

Molecular recognition of the beta-glucans laminarin and pustulan by a SusD-like glycan-binding protein of a marine Bacteroidetes.

FEBS J. 285(23):4465-4481
https://doi.org/10.1111/febs.14674

Kappelmann L, Krüger K, Hehemann JH, Harder J, Markert S, Unfried F, Becher D, Shapiro N, Schweder T, Amann RI, Teeling H. (2018)
Polysaccharide utilization loci of North Sea Flavobacteriia as basis for using SusC/D-protein expression for predicting major phytoplankton glycans.

ISME J. 13(1):76-91
https://doi.org/10.1038/s41396-018-0242-6

Francis BT, Krüger K, Fuchs BM, Teeling H, Amann RI. (2018)

Candidatus Prosiliicoccus vernus, a spring phytoplankton bloom associated member of the Flavobacteriaceae.

Syst. Appl. Microbiol. 42(1):41-53
https://doi.org/10.1016/j.syapm.2018.08.007

Unfried F, Becker S, Robb CS, Hehemann JH, Markert S, Heiden SE, Hinzke T, Becher D, Reintjes G, Krüger K, Avcı B, Kappelmann L, Hahnke RL, Fischer T, Harder J, Teeling H, Fuchs B, Barbeyron T, Amann RI, Schweder T. (2018)

Adaptive mechanisms that provide competitive advantages to marine bacteroidetes during microalgal blooms.

ISME J. 12(12):2894-2906
https://doi.org/10.1038/s41396-018-0243-5

Reisky L, Stanetty C, Mihovilovic MD, Schweder T, Hehemann JH, Bornscheuer UT. (2018)

Biochemical characterization of an ulvan lyase from the marine flavobacterium Formosa agariphila KMM 3901T.

Appl. Microbiol. Biotechnol. 102(16):6987-6996
https://doi.org/10.1007/s00253-018-9142-y

Chafee M, Fernàndez-Guerra A, Buttigieg PL, Gerdts G, Eren AM, Teeling H, Amann RI. (2018)

Recurrent patterns of microdiversity in a temperate coastal marine environment.

ISME J. 12(1):237-252
https://doi.org/10.1038/ismej.2017.165

Reisky L, Büchsenschütz HC, Engel J, Song T, Schweder T, Hehemann JH, Bornscheuer UT (2018)
Oxidative demethylation of algal carbohydrates by cytochrome P450 monooxygenases.
Nature Chem. Biol. 14(4):342-344
https://doi.org/10.1038/s41589-018-0005-8

Badur AH, Plutz MJ, Yalamanchili G, Jagtap SS, Schweder T, Unfried F, Markert S, Polz MF, Hehemann JH, Rao CV. (2017)
Exploiting fine-scale genetic and physiological variation of closely related microbes to reveal unknown enzyme functions.
J. Biol. Chem. 292(31):13056-13067
https://doi.org/10.1074/jbc.M117.787192

Hehemann JH, Truong LV, Unfried F, Welsch N, Kabisch J, Heiden SE, Junker S, Becher D, Thürmer A, Daniel R, Amann R, Schweder T. (2017)
Aquatic adaptation of a laterally acquired pectin degradation pathway in marine gammaproteobacteria.
Environ. Microbiol. 19(6):2320-2333
https://doi.org/10.1111/1462-2920.13726